|Typical Brand Names:
Colchicine was originally extracted from the autumn crocus but is now synthesised.
Colchicine binds to a substance (tubulin) found in white blood cells (leucocytes).
In gout, crystals of uric acid are deposited in certain joints. White blood cells migrate to the areas of the body where uric acid has been deposited. They attempt to engulf the crystals, and, as a result,lactic acid and pro-inflammatory enzymes are released. These substances give rise to the characteristic pain and swelling of gout.
Colchicine inhibits the migration of the white blood cells into the inflamed area, causing a reduction in pain and inflammation.
|Colchicine 0.6 mg - 30 Tabs
|Colchicine 0.6 mg - 60 Tabs
|Colchicine 0.6 mg - 90 Tabs
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Colchicine Directions To Use
Take the tablets by mouth. Follow the directions on the label of the prescription. Swallow the tablets with water. If you are taking it regularly to prevent attacks of gout, take exactly as directed. Do not take more often or in higher doses than directed.
If your doctor tells you to, increase the dose as directed when the first symptoms of a gouty attack occur. Reduce the dose as soon as the pain gets better or if nausea, vomiting, diarrhea, or stomach pains occur. Go back to your normal dose as soon as you can. If you only take the medication when you have a gouty attack, follow the above directions after the first symptoms appear.
Contact your doctor regarding the use of this medicine in children as special care may be needed.
Colchicine Warnings and Side Effects
Do not take Colchicine without first talking to your doctor if you are breast-feeding a baby. Talk to your doctor if you are or plan on becoming pregnant as this medicine may have harmful effects on the unborn baby.
Side effects that you should report to your doctor as soon as possible: blood in urine, difficulty breathing, fever, chills, or sore throat, muscle weakness, nausea, vomiting, numbness or tingling in hands or feet, pain or difficulty passing urine, skin rash, itching, stomach pain, swelling of the face or mouth, unusual bruising or bleeding, unusual weakness or tiredness.
Side effects that usually do not require medical attention (report to your doctor if they continue or are bothersome): diarrhea, loss of appetite, hair loss.
Colchicine Missed Dose
If you miss a dose, use it as soon as you remember. If it is near the time for the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep container tightly closed. Protect from light. Throw away any unused medication after the expiration date.
Symptoms of a colchicine overdose include nausea; vomiting; stomach pain; diarrhea; muscle weakness; burning in your throat, stomach, or skin; difficulty breathing; delirium; and seizures. An overdose of colchicine can result in death. If you suspect an overdose, seek immediate medical attention.
Colchicine More Information
Tell your doctor and pharmacist about all medicines that you are taking. Colchicine may interact with other drugs.
This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.