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Detrol LA

Classification: Heartburn
Generic Name: Tolterodine
Typical Brand Names: Detrol, Detrol LA

Tolterodine belongs to a class of drugs called cholinergic (acetyl-choline) receptor blockers. It is used to treat disorders of the urinary bladder that affect urination.

The urinary bladder is a muscular "bag." Urine coming from the kidneys fills the bladder and causes it to stretch like a balloon. As it stretches, pressure in the bladder increases and, when the bladder reaches a certain level of stretch, a desire to urinate is felt. Nerves in the muscular wall of the bladder release acetyl- choline, a chemical that attaches to receptors on the muscle cells and causes the cells to contract (tighten). This contributes further to the increase in pressure within the bladder and the desire to urinate. At the appropriate time (e.g., when a toilet is available), there is conscious relaxation of the muscle at the outlet of the bladder, and the high bladder pressure forces urine out of the bladder.

Normally, urination is under conscious control; however, in some individuals normal control as well as normal sensation are lost. The desire to urinate may be felt when there is little urine in the bladder, and urination may occur without warning or control. By blocking the effect of acetyl-choline on the muscle cells, tolterodine slows the build-up of pressure in the bladder, reduces the sensation to urinate, and prevents uncontrolled urination. The FDA approved tolterodine in 1998. An extended release form of tolterodine, (Detrol LA) was approved by the FDA in 2001.

Product Name Price
Detrol LA 2 mg - 30 Tabs $156.22
Detrol LA 2 mg - 60 Tabs $279.11
Detrol LA 2 mg - 90 Tabs $387.07
Detrol LA 4 mg - 30 Tabs $172.39
Detrol LA 4 mg - 60 Tabs $284.70
Detrol LA 4 mg - 90 Tabs $397.04
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Detrol LA Directions To Use

Take Detrol LA tablets by mouth. Follow the directions on the prescription label. Swallow the tablets with a drink of water. If you are taking the extended-release capsules, swallow them whole, do not crush, cut, or chew. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice.

Contact your doctor regarding the use of this medicine in children. Special care may be needed.

Detrol LA Warnings and Side Effects

Do not take Detrol LA if you have a blockage of the urinary tract (difficulty urinating); or a blockage in the intestines. Before taking Detrol LA, tell your doctor if you have liver disease; kidney disease; or glaucoma. You may not be able to take Detrol LA, or you may require a dosage adjustment or special monitoring if you have any of the conditions listed above. Detrol LA is in the FDA pregnancy category C. This means that it is not known whether Detrol LA will be harmful to an unborn baby. Do not take Detrol LA without first talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known whether Detrol LA will harm a nursing infant. Do not take Detrol LA without first talking to your doctor if you are breast-feeding a baby.

Serious side effects are not common. Side effects that you should report to your doctor as soon as possible: any signs of an allergic reaction, like itching or hives, blurred vision or difficulty focusing vision, confusion, difficulty passing urine, severe dizziness.

Side effects that usually do not require medical attention (report to your doctor if they continue or are bothersome): constipation, dry eyes, dry mouth, headache, mild dizziness or drowsiness, indigestion or stomach discomfort.

Detrol LA Missed Dose

If you miss a dose of this medicine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do NOT take 2 doses at once.

Detrol LA Storage

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Throw away any unused medicine after the expiration date.

Detrol LA Overdose

Seek emergency medical attention. Symptoms of Detrol LA overdose are not known but might include restlessness, tremor, irritability, seizures, delirium, hallucinations, flushing, fever, nausea, vomiting, a fast heartbeat and possibly coma.

Detrol LA More Information

Use caution when driving, operating machinery, or performing other hazardous activities. Detrol LA may cause dizziness, drowsiness, or blurred vision. If you experience dizziness, drowsiness, or blurred vision, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking Detrol LA. Avoid becoming overheated in hot weather. Detrol LA may increase the risk of heat stroke because it may decrease sweating. Drink plenty of fluid to maintain adequate hydration.

Detrol LA Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.