|Typical Brand Names:
Nexium tablets and injection contain the active ingredient esomeprazole, which is a type of medicine called a proton pump inhibitor. It acts in the stomach to decrease the production of stomach acid.
Proton pumps are found on cells that line the stomach and are used by these cells to produce stomach acid. Esomeprazole works by inhibiting the action of the proton pumps, and this reduces the production of stomach acid.
Acid is produced in the stomach as a normal part of the digestive process. However, in the condition known as gastro-oesophageal reflux disease or acid reflux, this acid is allowed to flow back into the food pipe (oesophagus), where it causes pain and a burning sensation known as heartburn. The acid can also irritate and cause inflammation of the lining of the foodpipe (reflux oesophagitis).
Esomeprazole reduces the production of stomach acid and thus reduces acid flowing back into the foodpipe. It is used to relieve the symptoms of gastro-oesophageal reflux disease, such as heartburn. It is also used to treat reflux oesophagitis, because stopping the acid flowing back into the foodpipe allows the lining of the foodpipe to heal. Esomeprazole is also used for the long-term management of people with healed oesophagitis, as suppressing the production of stomach acid helps prevent this condition recurring.
Esomeprazole is also used to treat ulcers in the stomach or upper intestine (peptic ulcers) that are associated with a type of bacteria called Helicobacter pylori. This type of bacteria is the most common cause of peptic ulcers. The bacteria cause the stomach to produce too much acid, which irritates the lining of the stomach and upper intestine and causes ulcers.
Esomeprazole is used in combination with antibiotics to eradicate Helicobacter pylori from the gut. The esomeprazole creates an environment in the gut in which the antibiotics can work effectively against the H pylori bacteria. The reduced acid in the gut allows the ulcer to heal, and both actions help prevent the ulcer from recurring.
|Nexium 20 mg - 30 Tabs
|Nexium 20 mg - 90 Tabs
|Nexium 40 mg - 30 Caps
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Nexium Directions To Use
Take Nexium capsules by mouth. Follow the directions on the prescription label. Swallow the capsules whole with a drink of water; do not crush, break or chew. The capsules can be opened and the contents sprinkled on applesauce or yogurt, given with fruit juices, or swallowed immediately with water. Do not crush the contents into the food. Nexium works best if taken on an empty stomach at least one hour before a meal. Take your doses at regular intervals. Do not take your medicine more often than directed.
Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.
Nexium Warnings and Side Effects
Before taking Nexium, tell your doctor if you have ever had any type of liver disease. You may not be able to take Nexium, or you may require a dosage adjustment or special monitoring. Nexium is in the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby. Do not take Nexium without first talking to your doctor if you are pregnant. It is not known whether Nexium passes into breast milk. Do not take Nexium without first talking to your doctor if you are breast-feeding a baby. Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients on penicillin therapy. These reactions are more apt to occur if you have a history of penicillin hypersensitivity and/or a history of sensitivity to multiple allergens. Pseudo membranous colitis has been reported with nearly all antibacterial agents, including clarithromycin and amoxicillin, and may range in severity from mild to life threatening. Therefore, it is important to consider this diagnosis in patients who present with diarrhea subsequent to the administration of antibacterial agents.
Side effects that you should report to your prescriber or health care professional as soon as possible: chest pain or tightness, dark yellow or brown urine, shortness of breath, skin rash, unusual tiredness or fatigue.
Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome): headache, diarrhea or constipation, flatulence (gas), nausea/vomiting, dry mouth.
Nexium Missed Dose
Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.
Store at 25°C (77°F); excursions permitted to 15 - 30°C (59 - 86°F). Keep container tightly closed. Dispense in a tight container if the product package is subdivided.
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include confusion, drowsiness, blurred vision, fast heartbeat, nausea, excessive sweating, flushing, headache, and dry mouth.
Nexium More Information
Some medicines or medical conditions may interact with Nexium. Notify your pharmacist or doctor of all prescription and over-the-counter medicine that you are taking. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.
This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.