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Zyban

Classification: Stop Smoking
Generic Name: Bupropion
Typical Brand Names: Wellbutrin, Wellbutrin SR, Wellbutrin XL, Zyban SR

Zyban tablets contain the active ingredient bupropion hydrochloride, which is a medicine used to help people who are dependant on nicotine to give up smoking. It acts in the brain but is not the same as nicotine replacement therapy.

It is not fully understood how this medicine works to help people give up smoking, but it is known that bupropion affects neurotransmitters in the brain. Neurotransmitters are chemicals that are stored in nerve cells and are involved in transmitting messages between the nerve cells.

Neurotransmitters are released from nerve cells as a message is transmitted. Once the message has been transmitted, the nerve cells then reabsorb the neurotransmitter.

Bupropion prevents two of these neurotransmitters, noradrenaline and dopamine, from being reabsorbed back into the nerve cells. Noradrenaline and dopamine are responsible for moderating mood and various other processes in the brain. It is thought that bupropion helps people to quit smoking by increasing the amount of noradrenaline and dopamine free to act in the brain.

Bupropion is used in combination with motivational support techniques. You should seek help and support as much as possible while giving up smoking, even while taking this medicine, as this will increase your chance of success.

You should start taking this medicine while you are still smoking and set a 'target stop date' for within the first two weeks of treatment, preferably in the first week. This is because the medicine needs time to start working.

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Zyban Directions To Use

Swallow Zyban whole. Do not crush or chew them or the sustained activity of the drug will be destroyed and the chances of side effects occurring may be increased. Take as directed, usually twice daily for 7 to 12 weeks. Do not take more or less medication than prescribed. Since this drug can cause sleeplessness at first, it is best not to take near bedtime. It is advised to continue smoking for the first week after starting this drug, until it reaches higher levels in your blood. Do not smoke if using any nicotine products with this drug. Too much nicotine can cause serious side effects. Do not stop taking Zyban without notifying your doctor.

Zyban Warnings and Side Effects

Do not take Zyban if you have taken a monoamine oxidase inhibitor (MAOI) in the last 14 days. Zyban is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Do not take Zyban without first talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known whether Zyban will be harmful to a nursing baby. Do not take Zyban without first talking to your doctor if you are breast-feeding a baby.

Zyban is generally well tolerated. Dry mouth, headache, increased sweating, nausea/vomiting, constipation, anxiety, fatigue and blurred vision may occur. If these effects persist or worsen, notify your doctor. Report: unusual weight loss or gain, palpitations, agitation, trouble sleeping. Unlikely but report promptly: tremor, dizziness, fainting, mood changes, slowed movements, difficulty urinating, decreased sex drive, drowsiness. Very unlikely but report promptly: seizures, mental problems, fever, muscle aches, yellowing of the eyes or skin. Notify your doctor immediately if an allergic reaction to this drug occurs. Symptoms include: difficulty breathing, rash, itching. If you notice other effects not listed above, contact your doctor or pharmacist.

Zyban Missed Dose

Take any missed Zyban dose as soon as possible but not if it is within 8 hours of the next dose. If it is time for the next Zyban dose, skip the missed dose and resume your regular schedule. Do not "double-up" the Zyban dose.

Zyban Storage

Store Zyban at room temperature, out of direct sunlight. Keep Zyban in a tightly closed container. Keep Zyban out of the reach of children.

Zyban Overdose

Seek emergency medical attention if an overdose is suspected. Symptoms of a Zyban overdose include seizures, hallucinations, loss of consciousness, weakness, a fast heartbeat, and heart attack.

Zyban More Information

Avoid alcohol or drink it only in moderation while taking Zyban. Alcohol may increase the risk of having a seizure while taking Zyban. However, if you usually drink a lot of alcohol, talk with your doctor before stopping. Suddenly stopping may increase the risk of having a seizure. Talk to your doctor about alcohol use before starting treatment with Zyban. Use caution when driving, operating machinery, or performing other hazardous activities. Zyban may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

Zyban Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.